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Shocking RA away? ear device aims to calm inflammation

NCT ID NCT06779123

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 23 times

Summary

This study tests a non-invasive device worn on the ear that sends mild electrical pulses to the vagus nerve, aiming to reduce inflammation in people with moderate-to-severe rheumatoid arthritis (RA). The trial includes 128 adults whose RA has not improved with standard biologic or targeted drugs. Participants will use the device daily for 12 weeks, and researchers will measure joint pain, swelling, and other symptoms to see if the treatment works better than a sham device.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center for Rheumatology, Academic Specialist Centre

    RECRUITING

    Stockholm, 17176, Sweden

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dept of Rheumatology, Umeå University Hospital

    RECRUITING

    Umeå, 90189, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dept of Rheumatology, Örebro University Hospital

    RECRUITING

    Örebro, 70116, Sweden

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Karolinska University Hospital

    RECRUITING

    Stockholm, 17176, Sweden

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Section for Rheumatology, Skåne University Hospital, Lund

    RECRUITING

    Lund, Skåne County, SE 22185, Sweden

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Section for Rheumatology, Skåne University Hospital, Malmö

    RECRUITING

    Malmö, 20502, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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