New injection could unpinch nerves in diabetic legs
NCT ID NCT07625020
First seen Jun 06, 2026 · Last updated Jun 23, 2026 · Updated 2 times
Summary
This study tests whether a single ultrasound-guided injection of medicine around compressed leg nerves can relieve numbness, pain, and weakness in people with diabetes. 266 participants will be randomly assigned to get the real injection or a sham (fake) injection, and neither they nor the researchers will know who got which. The main goal is to see if nerve function improves one month later.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The First Affiliated Hospital of Chongqing Medical University
RECRUITINGChongqing, Chongqing Municipality, 400016, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
mecobalamin and normal saline injection
What this could lead to
If it works, this could offer a new, minimally invasive way to relieve nerve compression symptoms in diabetic patients, potentially improving quality of life.
What could go wrong
This is a single-session procedure with a modest primary endpoint (1-point improvement on a scale). The sham control may show similar benefits, and long-term effects are unknown.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.