Nerve block showdown: which eases Post-Surgery pain best?
NCT ID NCT07001657
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two different nerve blocks—PECS II and SPSIP—to see which provides better pain relief after breast cancer surgery. 118 women received one of the blocks before surgery, and researchers measured how much opioid painkiller they needed in the first 24 hours. The goal is to find a more effective way to manage pain and reduce opioid use.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine hydrochloride
- What this could lead to
- If one block works better, it could mean less pain and fewer opioids after breast cancer surgery.
- What could go wrong
- This is a small, completed trial comparing two established techniques, so no major breakthrough is expected. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
118 people
The number who actually took part.
- Started
-
May 2025
- Finished
-
Jan 2026
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female patients aged 18-65 years * American Society of Anesthesiologists (ASA) physical status I-III * Body Mass Index (BMI) less than 35 kg/m² * Unilateral breast cancer surgery Exclusion Criteria: * Patient refusal to participate * BMI greater than or equal to 35 kg/m² * ASA physical status IV-V * Known allergy to any study medications * Pregnancy or breastfeeding * Presence of neuromuscular diseases * Chronic opioid use * Chronic pain syndromes * Significant organ failure (e.g., cardiac, hepatic, renal) * Contraindications to regional nerve blocks * Bilateral breast surgery
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Breast cancer are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Antalya Training and Research Hospital
Antalya, 07010, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a common steroid shield breast cancer patients from a dangerous drug side effect?
- Tiny magnetic seeds could guide surgeons to the right lymph node
- New PET tracer aims to light up hidden cancer targets
- Gut bacteria supplement tested against chemo hair loss
- Can a mindfulness program boost Self-Compassion in breast cancer survivors?
- Can a Decades-Old Anti-Inflammatory drug quiet the joint pain that drives women off breast cancer therapy?