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Nerve block before ankle surgery may cut pain and opioid use

NCT ID NCT07470021

Symptom relief Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether numbing specific nerves in the leg before ankle surgery can lower pain and help people recover faster. About 70 adults having ankle arthroscopy will receive either a nerve block or a placebo injection, along with standard anesthesia. Researchers will measure pain scores, opioid use, muscle strength, and how soon patients can walk, aiming to improve day-surgery experience.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Age between 18 and 65 years ASA physical status classification I-II Scheduled to undergo ankle arthroscopy under general anesthesia Expected to be available for follow-up on the day of surgery (day-case or short-stay surgery) Able to understand the procedures and methods of the clinical trial and voluntarily provide written informed consent Body mass index (BMI) between 16 and 32 kg/m² Exclusion Criteria: History of severe ankle nerve injury or peripheral neuropathy Severe cardiac, pulmonary, hepatic, or renal dysfunction Chronic pain or regular use of opioid analgesics for more than 3 months History of extensive ankle or lower leg surgery that may affect nerve localization Psychiatric disorders or cognitive impairment that preclude accurate NRS pain scoring Pregnancy or breastfeeding Known allergy or contraindication to any of the study drugs Any other condition deemed unsuitable for inclusion by the investigators

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Conditions

The condition(s) this trial relates to.

ankle injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ankle ligament injury，chronic ankle instability，ankle arthroscopy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, China