Could a steroid nerve block ease pain after fibroid procedure?
NCT ID NCT04126824
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether adding a steroid to a nerve block can better control pain after a procedure that treats uterine fibroids or adenomyosis. About 28 women aged 30 to 60 will receive either a standard numbing nerve block or one with added steroids. Researchers will measure pain levels and painkiller use afterward to see if the steroid helps.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- triamcinolone (steroid) and bupivacaine (numbing medicine) given as a nerve block
- What this could lead to
- If it works, this could lead to a better way to manage pain after uterine artery embolization, reducing the need for strong painkillers.
- What could go wrong
- This is a very small, early-phase trial with only 28 participants, so results may not apply to everyone. Adding steroids may not improve pain control and could carry risks like infection or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
-
28 people
The number who actually took part.
- Started
-
Jan 2022
- Expected to finish
-
Aug 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
30 to 60 years
- Sex
-
Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * females * aged between 30 and 60 years * diagnosed with symptomatic uterine fibroids and/or adenomyosis and scheduled to undergo UAE procedure Exclusion Criteria: * Contraindications to UAE * SHNB is deemed unsafe for the patient * Allergies to local anesthetic or steroid agent * History of inflammatory bowel disease or ulcerative colitis * Uncorrectable abnormal coagulation profile * Diabetes mellitus
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of California, Los Angeles
Westwood, Los Angeles, California, 90024, United States
-
University of North Carolina
Chapel Hill, North Carolina, 27599, United States
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Other studies related to the condition(s) this trial covers.
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