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Could a steroid nerve block ease pain after fibroid procedure?

NCT ID NCT04126824

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether adding a steroid to a nerve block can better control pain after a procedure that treats uterine fibroids or adenomyosis. About 28 women aged 30 to 60 will receive either a standard numbing nerve block or one with added steroids. Researchers will measure pain levels and painkiller use afterward to see if the steroid helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
triamcinolone (steroid) and bupivacaine (numbing medicine) given as a nerve block
What this could lead to
If it works, this could lead to a better way to manage pain after uterine artery embolization, reducing the need for strong painkillers.
What could go wrong
This is a very small, early-phase trial with only 28 participants, so results may not apply to everyone. Adding steroids may not improve pain control and could carry risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

28 people

The number who actually took part.

Started

Jan 2022

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 60 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * females * aged between 30 and 60 years * diagnosed with symptomatic uterine fibroids and/or adenomyosis and scheduled to undergo UAE procedure Exclusion Criteria: * Contraindications to UAE * SHNB is deemed unsafe for the patient * Allergies to local anesthetic or steroid agent * History of inflammatory bowel disease or ulcerative colitis * Uncorrectable abnormal coagulation profile * Diabetes mellitus

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, Los Angeles

    Westwood, Los Angeles, California, 90024, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27599, United States

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