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Throat numb shot may soothe vocal cord surgery recovery

NCT ID NCT06734975

Symptom relief Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a numbing injection (nerve block) given during vocal cord surgery can reduce pain, coughing, and improve voice recovery afterward. About 28 adults with benign vocal cord growths will receive either the numbing medicine or a saltwater placebo. Researchers will track pain scores, cough severity, and voice quality in the days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine and triamcinolone acetonide
What this could lead to
If it works, this could provide a simple way to reduce pain and coughing after vocal cord surgery, helping patients recover more comfortably.
What could go wrong
This is a small early-phase trial with only 28 people, so results may not apply to everyone. The injection itself carries minor risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 28 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient is aged 18 years or older at time of consent * Patient has suspected or confirmed benign vocal fold lesion * Patient is planning to undergo direct laryngoscopy with excision of the vocal fold lesion * Patient is English or Spanish speaking * Patient is not pregnant per self report * Patient is not incarcerated Exclusion Criteria: * Patient is not 18 years of age or older at consent date * Patient does not speak English or Spanish * Patient is currently pregnant or plans to become pregnant prior to their study procedure * Patient has a laryngeal malignancy or found to find a laryngeal malignancy on final pathology * Patient will not be undergoing direct laryngoscopy with excision of lesion * Patient is unable to provide consent or complete study activities * Patient is incarcerated

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Conditions

The condition(s) this trial relates to.

laryngeal disorder polyp of vocal cord

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Vocal cord cyst Vocal cord disease Vocal cord polyp

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Rutgers New Jersey Medical School

    RECRUITING

    Newark, New Jersey, 07103, United States

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