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Which nerve block is best for knee surgery recovery?

NCT ID NCT05190120

Symptom relief Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two types of nerve blocks—femoral and adductor canal—for people having knee arthroscopy (like ACL repair or meniscus surgery). The goal was to see which block provides better pain control while keeping the quadriceps muscle strong. 132 participants received one of the two blocks before surgery, and their muscle strength and pain scores were measured. The results could help guide which block to use for faster recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ropivacaine
What this could lead to
If successful, this could help doctors choose a nerve block that provides good pain relief while preserving leg strength after knee surgery.
What could go wrong
This is a small, completed Phase 4 study with 132 participants. Results may not apply to all patients or surgeries. Both blocks are already used in practice, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

132 people

The number who actually took part.

Started

Jan 2016

Finished

Mar 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * American Society of Anesthesia I-III classification, * Scheduled for arthroscopic knee surgery (meniscal debridement/repair, ACL reconstruction) Exclusion Criteria: * Age younger than 18 years * Non-English speaking * Any contraindication for regional anesthesia, such as allergy to local anesthetics or opioids, -Coagulopaty or severe thrombocytopenia * Infection at puncture sites * Pre-existing neuropathy in operative limb * Need for post-operative nerve function monitoring * Dementia * Patient refusal * High pre-operative opioid requirements

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament tear Knee meniscus tear

Contacts and locations

Locations

  • UCSF Orthopedic Trauma Service

    San Francisco, California, 94158, United States

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Other studies related to the condition(s) this trial covers.