Which nerve block eases kidney surgery pain best? a Head-to-Head trial
NCT ID NCT07726550
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This trial compares two ultrasound-guided nerve block techniques—erector spinae plane block and modified external oblique intercostal plane block—for controlling pain after open kidney surgery. Sixty adults scheduled for elective open nephrectomy will receive one of the two blocks before surgery, and researchers will measure pain scores, opioid use, and side effects over the first 24 hours. The goal is to see which approach provides better pain relief and recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- two ultrasound-guided nerve block procedures: erector spinae plane block and modified external oblique intercostal plane block, using bupivacaine
- What this could lead to
- If one nerve block proves superior, it could become the preferred method for managing pain after open kidney surgery, potentially reducing opioid use and improving recovery.
- What could go wrong
- This is a small, early-stage trial with only 60 participants, so results may not apply to all patients. Both techniques are already in use, so the difference may be small.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18 and 65 years. * American Society of Anesthesiologists (ASA) physical status I or II. * Scheduled for elective open nephrectomy. * Able and willing to provide written informed consent. * Willing to comply with study procedures. Exclusion Criteria: * Refusal to participate or inability to provide informed consent. * Emergency surgery. * Body mass index (BMI) greater than 35 kg/m². * Known allergy or hypersensitivity to local anesthetics. * Infection at the planned block insertion site. * Coagulopathy or ongoing anticoagulant therapy. * Pregnancy or breastfeeding. * Prisoners or other vulnerable populations unable to provide independent consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tekirdağ Namık Kemal University
Tekirdağ, Tekirdağ, 59000, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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- Can a nerve block quiet the brain during gallbladder surgery?