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Nerve block showdown: which injection stops chronic pain after breast surgery?

NCT ID NCT07674836

Symptom relief Sponsor: Engin Çetin Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This trial compares two types of nerve blocks given before breast surgery to see which better prevents chronic pain that can last for months. Women aged 18-65 scheduled for mastectomy will receive either a serratus posterior superior intercostal plane block or an erector spinae plane block. The study measures pain severity and interference three months after surgery using a standard questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nerve block (bupivacaine)
What this could lead to
If one block proves better, it could become the standard method to prevent long-term pain after breast surgery.
What could go wrong
This is a small, early-stage comparison. Results may not apply to all patients, and both blocks carry risks like infection or allergic reaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients aged 18-65 years * ASA physical status I-III * Body mass index (BMI) between 18 and 35 kg/m² * Scheduled for elective unilateral breast surgery (mastectomy with or without sentinel lymph node biopsy) * Ability to understand and provide written informed consent Exclusion Criteria: * Infection at the site of block application * Known allergy to local anesthetics * Coagulopathy or anticoagulant therapy * Chronic opioid use * Pregnancy * Inability to communicate or cooperate * Refusal to participate * Failed block * Requirement of additional intraoperative analgesia outside the study protocol * Development of serious intraoperative complications

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Conditions

The condition(s) this trial relates to.

opiate dependence opioid abuse Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid use Postoperative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Health Sciences Kocaeli City Hospital

    RECRUITING

    İzmit, Kocaeli, 41200, Turkey (Türkiye)

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