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A simple pain block might shield aging hearts during hip surgery

NCT ID NCT07751146

Disease control Sponsor: Tongji Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This study looks at whether a single nerve block, given before surgery, can reduce the risk of heart muscle damage in older adults who have hip fracture surgery more than 48 hours after injury. Researchers will review medical records of 500 patients aged 65 and older, comparing those who received a nerve block with those who did not. The main focus is on whether the nerve block lowers the rate of heart injury during the hospital stay, which could offer a simple way to improve outcomes for this high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Peripheral nerve block (a single injection to numb nerves around the hip before surgery)
What this could lead to
If effective, this simple pain-blocking procedure could become a standard way to protect the hearts of older hip fracture patients who face delayed surgery, potentially reducing complications and deaths.
What could go wrong
This is a retrospective review, not a controlled experiment, so it can only show associations, not proof. The results may be influenced by other factors, and the nerve block's heart-protective effect remains uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients aged 65 or above who underwent hip fracture surgery at Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology from January 1, 2019 to December 31, 2025, and whose injury occurred more than 48 hours before the surgery

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 65 years * Radiological evidence of non-pathological hip fractures (femoral neck, intertrochanteric or subtrochanteric fractures) * Time from injury to surgery \> 48 hours * Underwent general anesthesia or intraspinal anesthesia * Had at least one troponin I/T test result during preoperative or postoperative hospitalization Exclusion Criteria: * Preoperative presence of acute myocardial infarction (onset \< 7 days), acute heart failure or sepsis * Multiple fractures or concurrent surgeries at other sites * Neuroblock as the sole anesthesia method * Continuous nerve block or epidural analgesia * Severe lack of key variables

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Conditions

The condition(s) this trial relates to.

hip fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hip fracture Myocardial injury after noncardiac surgery Perioperative myocardial injury

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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