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A cheap blood marker might flag delirium risk in elderly surgery patients

NCT ID NCT07741175

Knowledge-focused Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study asks whether a routine blood test measure called the neutrophil-lymphocyte ratio (NLR) can help predict delirium—a state of sudden confusion—in older adults after hip fracture surgery. Delirium is a common and serious complication in elderly patients, and inflammation may play a role. Researchers will track 100 patients aged 65 and older, measuring NLR from standard blood counts and checking for delirium using a validated assessment tool. If NLR proves useful, it could offer a simple, inexpensive way to identify high-risk patients earlier.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
neutrophil-lymphocyte ratio (NLR) blood test
What this could lead to
If NLR proves reliable, it could become a simple, low-cost tool to identify older patients at higher risk of delirium after hip surgery, enabling earlier monitoring and preventive care.
What could go wrong
This is a single-center study with 100 participants, and NLR is a general inflammation marker that may not be specific enough to predict delirium reliably in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Feb 2022

Finished

Oct 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients aged 65 and over, with a Mini Mental Test (MMT) score of 24 and above, who would undergo hip fracture surgery, who -or their legal guardian- could give voluntary consent, with ASA scores of I-IV.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 65 and over * Patients who will undergo hip fracture surgery * Patients who or their relatives can give voluntary consent * ASA I-IV patients * Patients with a Preoperative Mini Mental Test (MMT) score of 24 and above Exclusion Criteria: * Under 65 years old * Patients who did not agree to participate in the study * Unconscious * Patients with a preoperative Mini Mental Test (MMT) score below 24 * Visually, hearing and speech impaired * Chronic alcohol user * Patients with cognitive or psychiatric disorders such as known dementia, Parkinson's, Alzheimer's * Patients who need postoperative mechanical ventilation support * A history of acute myocardial infarction in the last 6 months * Patients with chronic renal failure undergoing regular dialysis * Patients using oxygen concentrators at home

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Conditions

The condition(s) this trial relates to.

delirium hip fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Delirium Elderly patient Hip fracture surgery Neutrophil lymphocyte ratio

Contacts and locations

Locations

  • Ali Emre Karakis

    Ankara, 06200, Turkey (Türkiye)

  • Dr. Abdurrahman Yurtaslan OTRH

    Ankara, Turkey (Türkiye)

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