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New drug combo aims to tame advanced breast cancer with fewer side effects

NCT ID NCT03377387

First seen May 01, 2026 · Last updated May 01, 2026

Summary

This study tests a different, experimental dosing schedule of the chemotherapy drug capecitabine combined with the targeted drug neratinib in people with advanced HER2-positive breast cancer. The goal is to find the safest dose that still works. About 34 adults with stage IV breast cancer will participate to see if this new schedule causes fewer side effects than the standard approach.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baptist Alliance - McI

    Miami, Florida, 33143, United States

  • Hartford Healthcare Cancer Institute @ Hartford Hospital

    Hartford, Connecticut, 06102, United States

  • Lehigh Valley Health Network

    Allentown, Pennsylvania, 18103, United States

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester

    Harrison, New York, 10604, United States

  • Memorial Sloan Kettering at Basking Ridge

    Basking Ridge, New Jersey, 07920, United States

Conditions

Explore the condition pages connected to this study.