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Hope for kids with scarred lungs: new drug trial launches

NCT ID NCT07366034

First seen Feb 01, 2026

Summary

This study tests a medicine called nerandomilast in children aged 2 to 17 with fibrosing interstitial lung disease, a condition where lung tissue becomes scarred and stiff. The goal is to see if the drug is safe and how the body processes it, and to get early signs of whether it helps lung function. Some children will receive the drug, others a placebo for 6 months, then all get the drug for at least 2 more years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aarhus University Hospital

    Aarhus N, 8200, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Alberta Children's Hospital

    Calgary, Alberta, T3B 6A8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Amsterdam University Medical Center

    Amsterdam, 1105 AZ, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Aristotle University, Thessaloniki

    Thessaloniki, 54642, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Associação dos Funcionários Públicos do Estado do Rio Grande do Sul - Hospital Ernesto Dorneles

    Porto Alegre, 90160-093, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing Children's Hospital, Capital Medical University

    Beijing, 100045, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Birmingham Children's Hospital

    Birmingham, B4 6NH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Brussels - UNIV HUDERF

    Brussels, 1020, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centro de Investigacion Clinica y Medicina Traslacional (CIMeT)

    Guadalajara, 44340, Mexico

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centro de Pesquisa Clinica do Instituto da Crianca - HCFMUSP

    São Paulo, 5403-900, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Charité - Universitätsmedizin Berlin

    Berlin, 13353, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fukuoka Children's Hospital

    Fukuoka, Fukuoka, 813-0017, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fundacion Respirar

    CABA, 1426, Argentina

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOP Armand-Trousseau

    Paris, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOP Femme Mère Enfant

    Bron, 69677, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOP Intercommunal

    Créteil, 94000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOP Necker - Enfants Malades

    Paris, 75015, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOP Timone

    Marseille, 13387, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HUS Lasten ja nuorten sairaudet, Kliinisen tutkimuksen yksikkö

    Helsinki, PL 281, 00029, Finland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hamburger Zentrum für Kinder- und Jugendrheumatologie

    Hamburg, 22081, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Virgen del Rocío

    Seville, 41013, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital de Pediatria Prof. Dr. Juan P. Garrahan

    CABA, C1245AAM, Argentina

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hunan Provincial People's Hospital

    Changsha, 410005, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IMIP Pernambuco

    Recife, 50070-550, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Istituto G. Gaslini

    Genova, 16147, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Johns Hopkins Hospital

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • King's College Hospital

    London, SE5 9RS, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Center for Child Health and Development

    Tokyo, Setagaya-ku, 157-8535, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Osaka Women's and Children's Hospital

    Osaka, Izumi, 594-1101, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale Pediatrico Bambino Gesù

    Roma, 00165, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seoul National University Hospital

    Seoul, 03080, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Serviços Medicos Respirar Sul Fluminense

    Barra Mansa, 27323240, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tampere University Hospital

    Tampere, 33520, Finland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Children's Hospital of Fudan University

    Shanghai, 201102, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ULS de Santa Maria, E.P.E

    Lisbon, 1649-035, Portugal

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Clinical Center of the Medical University of Warsaw

    Warsaw, 02 091, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Motol

    Prague, 150 00, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Minnesota

    Minneapolis, Minnesota, 55454, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

pulmonary fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.