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20-Year review aims to improve surgery for rare childhood kidney cancer

NCT ID NCT05195411

Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked back at 72 children treated for Wilms tumor (a kidney cancer) that had spread into the vena cava, the large vein carrying blood to the heart. Researchers reviewed medical records from 1999 to 2019 to understand how surgery was managed and what complications occurred. The goal is to create better surgical guidelines for this rare and complex condition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could lead to clear surgical guidelines for treating children with Wilms tumor that has spread into the vena cava, potentially improving outcomes.
What could go wrong
This is a retrospective review of past cases, not a new treatment trial. It cannot prove that any specific approach works better than another.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

72 people

The number who actually took part.

Started

Dec 2022

Finished

Mar 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children with nephroblastoma with vena cava thrombosis +/- atrial extension cared between 1999 and 2019 in Parisian hospitals: Necker and Bicêtre.

Ages

Up to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Minors with nephroblastoma with vena cava thrombosis +/- atrial extension. * Cared between 1999 and 2019 in the centers of the study. Exclusion Criteria: \- Other renal and non-renal tumors with vena cava thrombosis.

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Conditions

The condition(s) this trial relates to.

kidney Wilms tumor Wilms tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nephroblastoma with vena cava thrombosis

Contacts and locations

Locations

  • Hôpital Kremlin Bicêtre

    Le Kremlin-Bicêtre, 94270, France

  • Hôpital Necker-Enfants Malades

    Paris, 75015, France