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Could adding immunotherapy to chemotherapy shrink colorectal tumors better?

NCT ID NCT06154538

First seen Jan 06, 2026 · Last updated May 20, 2026 · Updated 23 times

Summary

This study tests whether adding immune checkpoint inhibitors to standard chemotherapy before surgery can improve outcomes for people with locally advanced colorectal cancer. About 170 adults with stage II/III colorectal cancer will be randomly assigned to receive either the combination or chemotherapy alone. The main goal is to see if the combination leads to a higher rate of complete tumor disappearance at the time of surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital/ National Cancer Center, Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, Beijing Municipality, 100038, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Qilu Hospital of Shandong University

    RECRUITING

    Jinan, Shandong, 250000, China

    Contact

    Contact

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.