Vacuum dressing may cut infections after stoma reversal
NCT ID NCT07258134
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a special vacuum dressing (negative pressure wound therapy) helps wounds heal better after stoma reversal surgery compared to letting them heal naturally. 72 adults were randomly assigned to one of the two methods. Researchers checked for infection and scar quality in the days and weeks after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- negative pressure wound therapy (a vacuum dressing device)
- What this could lead to
- If it works, this could offer a better way to heal surgical wounds after stoma reversal, reducing infections and improving scar appearance.
- What could go wrong
- This is a small, single-center study with only 72 participants, so results may not apply to everyone. The therapy is a procedure, not a drug, and benefits may be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
72 people
The number who actually took part.
- Started
-
Feb 2025
- Finished
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Aug 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: All patients aged between 18-80 years undergoing stoma reversal surgery were included, following their formal consent for inclusion in the study protocol. Exclusion Criteria: * Patients with history of prolonged antibiotic use prior to stoma reversal surgery (\>1months). * Patients with prior skin condition that required medical treatment (for instance, Plaque Psoriasis). * Patient with prior history of wound-related complication (like keloids or hypertrophic scars). Furthermore, after allocation, the patients with the following protocol violations were also excluded: * Patients who had undergone any other forms of wound closure after stoma reversal, that deviated from the study protocol. * Patients who were re-operated during the hospital stay for any other reason than surgical site infection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sindh Institute of Urology and Transplantation
Karachi, Sindh, 74200, Pakistan
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