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Could a pill help people who are losing their speech?

NCT ID NCT07033481

First seen Apr 08, 2026 · Last updated May 25, 2026 · Updated 11 times

Summary

This early study tests a drug called neflamapimod in 20 people with a rare brain condition that slowly destroys the ability to speak (primary progressive aphasia). The main goal is to check safety and see if the drug can improve language symptoms. Participants take the drug for several weeks and are monitored for side effects and changes in speech.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Ageing Research Unit, Campus for Ageing and Vitality, Biomedical Research Building

    RECRUITING

    Newcastle upon Tyne, NE4 5PL, United Kingdom

    Contact Email: •••••@•••••

  • Columbia University

    ACTIVE_NOT_RECRUITING

    New York, New York, 10032, United States

  • Hospital of the University of Pennsylvania

    ACTIVE_NOT_RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Mayo Clinic

    ACTIVE_NOT_RECRUITING

    Rochester, Minnesota, 55905, United States

  • Northwestern Memorial Hospital

    ACTIVE_NOT_RECRUITING

    Chicago, Illinois, 60611, United States

  • The Ohio State University

    ACTIVE_NOT_RECRUITING

    Columbus, Ohio, 43221, United States

  • Windsor Research Unit, Fulbourn Hospital

    RECRUITING

    Cambridge, CB21 5EF, United Kingdom

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.