Can a tailored therapy help young people overcome the stigma of psychosis?
NCT ID NCT04889911
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This trial tests a modified therapy called NECT-YA, designed for young people aged 15-24 who have recently experienced a first episode of psychosis. The therapy aims to reduce self-stigma and improve how they see themselves, which may help them stay engaged in treatment. Participants receive NECT-YA alongside standard Coordinated Specialty Care, and the study compares this combination to standard care alone. The goal is to see if the adapted therapy is feasible, acceptable, and shows promise in improving treatment engagement and well-being.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Narrative Enhancement and Cognitive Therapy adapted for young adults (NECT-YA), combined with Coordinated Specialty Care (CSC)
- What this could lead to
- If successful, this could provide a tailored therapy to help young people recovering from psychosis feel less stigmatized and stay engaged in their care.
- What could go wrong
- This is a small, early-stage study focused on feasibility and preliminary effects, so results may not be definitive or widely applicable. The therapy is new and may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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17 people
The number who actually took part.
- Started
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Aug 2023
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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15 to 24 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Meets criteria for FEP youth based on the following definition: age 15-24, onset of psychotic symptoms within the last 5 years, and an absence of a primary substance use or mood disorder that could be causing the psychotic symptoms (confirmed by program eligibility); 2. Meets criteria for moderate (defined as a mean score of 1-1.5 on the 0-3 scale of the Internalized Stigma of Mental lllness Scale \[ISMI\]) or elevated (defined as a mean score of 1.5-3 on the 0-3 scale of the ISMI) self-stigma; 3. Speaks English well enough to complete assessments and participate in groups; 4. Is able to provide informed consent to participate. Exclusion Criteria: Does not meet any of the above inclusion criteria.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Eskenazi Health, PARC Program
Indianapolis, Indiana, 46202, United States
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