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Tiny study hints neck surgery may help in advanced throat cancer

NCT ID NCT07180173

Knowledge-focused Sponsor: Taichung Veterans General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at 7 patients with advanced nasopharyngeal carcinoma (stage N3) to see if doing neck dissection (surgery to remove lymph nodes) before radiation therapy could improve outcomes. The goal was to understand if this approach reduces the chance of cancer coming back or spreading. Because it is a small, retrospective study, it can only suggest possibilities, not provide firm answers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could point toward a treatment strategy that improves survival for patients with advanced nasopharyngeal carcinoma.
What could go wrong
This is a very small, retrospective study with only 7 patients, so results may not apply to everyone. It looks back at past data, so it cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

7 people

The number who actually took part.

Started

Apr 2007

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population includes adult patients aged 18 years or older with pathologically confirmed nasopharyngeal carcinoma (NPC), staged as Stage IV (Tany N3) according to the 8th edition of the AJCC staging system. All participants have completed definitive concurrent chemoradiotherapy (CCRT) or induction chemotherapy (IC) followed by radiotherapy/CCRT, and have complete clinical imaging and medical records before and after treatment for subsequent efficacy and prognostic analysis. This cohort represents high-risk patients with advanced nodal disease, characterized by increased risks of both locoregional recurrence and distant metastasis, making them suitable for evaluating current treatment outcomes and subsequent management strategies.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years. * Pathologically confirmed diagnosis of nasopharyngeal carcinoma (NPC). * Stage IV disease (Tany N3) according to the 8th edition of the AJCC staging system. * Completion of definitive concurrent chemoradiotherapy (CCRT), or induction chemotherapy (IC) followed by radiotherapy/CCRT. * Availability of complete clinical imaging and medical records before and after treatment for efficacy and prognostic analysis. Exclusion Criteria: * Presence of distant metastasis at initial diagnosis. * Prior history of treatment for other head and neck malignancies, aside from definitive therapy for NPC (to avoid confounding prognosis). * Incomplete or prematurely discontinued definitive radiotherapy, resulting in failure to complete the planned curative treatment. * Lack of complete pathology report, clinical imaging, or treatment records, making effective analysis impossible.

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Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Oncology Radiology

Contacts and locations

Locations

  • Taichung Veterans General Hospital

    Taichung, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.