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Blood test may predict Post-Surgery pain, study hints

NCT ID NCT07353138

Knowledge-focused Sponsor: Istinye University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a routine blood test taken before septorhinoplasty (nose surgery) can help predict how much pain a person will feel right after the operation. Researchers will check the ratio of two types of white blood cells (neutrophils and lymphocytes) and other blood markers, then compare them to pain scores reported by patients in the recovery room. No new treatments or changes to standard care are involved—this is purely an observational study to gather information.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 110 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients aged 18-65 years who undergo elective septorhinoplasty under general anesthesia. All participants are managed according to standard clinical practice and are admitted to the Post-Anesthesia Care Unit (PACU) postoperatively, where early pain assessments and routine clinical monitoring are performed. Eligible patients have a complete preoperative hemogram obtained within 30 days prior to surgery and comprehensive postoperative records, including pain scores and vital signs. Patients with conditions or treatments that could significantly affect inflammatory markers or pain perception are excluded to ensure a homogeneous study population

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18-65 years * Patients undergoing elective septorhinoplasty * Surgery performed under general anesthesia * Complete recording of early postoperative VAS pain scores, Aldrete scores, NUDES scores, and vital signs in the Post-Anesthesia Care Unit (PACU) * Preoperative complete blood count (hemogram) performed within 30 days prior to surgery * Clinical records and hospital information system data that are complete, accessible, and adequate for analysis Exclusion Criteria: * Patients undergoing emergency surgery * Septorhinoplasty combined with additional major surgical procedures (e.g., advanced ENT or maxillofacial surgery) * Presence of known hematological disease, active infection, immunosuppressive therapy, or advanced liver or renal failure * Chronic opioid use or regular analgesic medication use in the preoperative period * History of significant clinical events between the preoperative hemogram and surgery that could alter inflammatory status (e.g., infection, hospitalization, additional surgery) * Incomplete or missing data regarding preoperative hemogram parameters or PACU pain scores

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neutrophil to lymphocyte ratio Septorhinoplasty

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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More trials for these conditions

Other studies related to the condition(s) this trial covers.