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Experimental combo for tough head and neck cancer shows early promise but trial stopped

NCT ID NCT04862455

First seen Nov 21, 2025 · Last updated Apr 30, 2026 · Updated 13 times

Summary

This study tested a new approach for people with head and neck cancer that had spread or come back. It combined an experimental drug (NBTXR3) activated by radiation with an immunotherapy drug (pembrolizumab). The goal was to see if this combination could shrink tumors and improve survival. Only 14 people enrolled before the study was ended early.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

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