20,000 heart patients enrolled in major artery study
NCT ID NCT01366404
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows about 20,000 people with coronary artery disease who had a special test called FFR to guide their artery-opening procedure. Researchers want to see how these patients' heart health changes over 2 years. The goal is to better understand the long-term results of this treatment approach.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 20,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2011
- Expected to finish
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Apr 2037
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who had FFR measurement
- Ages
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35 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 35 years and older * FFR measurement on one and more coronary artery stenosis * Willing and able to provide informed, written consent Exclusion Criteria: * Stenosis with TIMI\<3 flow * Graft vessel * Ejection fraction \< 30% * Angiographic evidence of extreme tortuosity or calcified coronary vessels * Suspected coronary spasm even after sufficient nitrate injected * Life expectancy \<2 year * Planned cardiac surgery or planned major non cardiac surgery * Woman who are breastfeeding, pregnant or planning to become pregnant during the course of the study Imaging study specific exclusion criteria * visually-estimated angiographic reference segment diameter of \<2.75mm or \>4.0mm * Inappropriate for IVUS/VH/OCT procedures : inability for imaging wire or catheter to pass through the tight stenosis, severe calcification, angulation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
29 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Asan Medical Center
RECRUITINGSeoul, South Korea
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Chonnam National University Hospital
RECRUITINGGwangju, South Korea
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Chungbuk National University Hospital
RECRUITINGCheongju-si, South Korea
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Chungnam National University Hospital
RECRUITINGDaejeon, South Korea
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Daegu Catholic University Center
RECRUITINGDaegu, South Korea
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Dong-A Medical Center
RECRUITINGPusan, South Korea
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Gangnam Severance Hospital
RECRUITINGSeoul, South Korea
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Gangneung Asan Hospital
RECRUITINGGangneung, South Korea
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Gangwon National Univ. Hospital
RECRUITINGChuncheon, South Korea
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Hallym University Kangdong Sacred Heart Hospital
RECRUITINGSeoul, South Korea
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Hallym University Sacred Heart Hospital
RECRUITINGAnyang, South Korea
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Inje University Ilsan Paik Hospital
RECRUITINGIlsan, South Korea
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Keimyung University Dongsan Medical Center
RECRUITINGDaegu, South Korea
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Korea University Anam Hospital
RECRUITINGSeoul, South Korea
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Korea University Guro Hospital
RECRUITINGSeoul, South Korea
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Kyung-Hee University Hospital at Kangdong
RECRUITINGSeoul, South Korea
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Kyungpook National university hospital
RECRUITINGDaegu, South Korea
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Pusan National University Hospital
RECRUITINGPusan, South Korea
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Pusan National University Yangsan Hospital
RECRUITINGYangsan, South Korea
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Seoul National University Boramae Medical Center
RECRUITINGSeoul, South Korea
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Seoul National University Hospital
RECRUITINGSeoul, South Korea
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Seoul university Bundang hospital
RECRUITINGSeongnam, South Korea
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Soon Chun Hyang University Hospital Bucheon
RECRUITINGBucheon-si, South Korea
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The Catholic University of Korea, Deajeon St.Mary's hospital
RECRUITINGDaejeon, South Korea
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The Catholic University of Korea, Seoul St.Mary's Hospital
RECRUITINGSeoul, South Korea
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The Catholic University of Korea, Yeouido St. Mary's Hospital
RECRUITINGSeoul, South Korea
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Ulsan University Hospital
RECRUITINGUlsan, South Korea
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Wonju Severance Christian Hospital
RECRUITINGWŏnju, South Korea
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Yeungnam University Medical Center
RECRUITINGDaegu, South Korea
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