Urine test could guide heart failure treatment and save lives
NCT ID NCT07558798
First seen Apr 30, 2026 · Last updated Jun 23, 2026 · Updated 11 times
Summary
This study tests whether adjusting diuretic doses based on urine sodium levels improves outcomes for people hospitalized with acute heart failure and severe fluid buildup. About 270 participants will be randomly assigned to either standard care or a strategy where diuretic doses are doubled if urine sodium is low. The goal is to see if this approach reduces deaths, hospital readmissions, and length of stay.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Akershus University Hospital
Lørenskog, Akershus, 1478, Norway
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Østfold Hospital Trust
Sarpsborg, Østfold fylke, 1714, Norway
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
loop diuretics (e.g., furosemide)
What this could lead to
If successful, this approach could reduce deaths, hospital readmissions, and hospital stays for people with severe heart failure.
What could go wrong
This is a relatively small, early-stage study (270 participants) that has not yet started. The benefit may be modest or not apply to all patients, and the urine-sodium monitoring adds complexity to care.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.