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Can oxygen during exercise supercharge lung rehab for ILD patients?

NCT ID NCT07679854

Symptom relief Sponsor: Frédéric Hérengt Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This trial investigates whether adding high-flow nasal oxygen during exercise training can improve endurance and quality of life for people with chronic fibrotic interstitial lung disease (ILD). Participants undergo a 4-week pulmonary rehabilitation program, receiving either high-flow oxygen or standard oxygen during cycling exercises. The study measures how long they can exercise at a constant workload, along with walking distance and breathing comfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-flow nasal oxygen
What this could lead to
If it works, this approach could make pulmonary rehabilitation more effective for people with ILD, helping them exercise longer and breathe easier.
What could go wrong
This is a small, early-stage trial with 60 participants. The benefits may be modest, and high-flow oxygen may not be practical or comfortable for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Aug 2022

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years. * Confirmed diagnosis of interstitial lung disease (ILD). * Indication for pulmonary rehabilitation according to current guidelines, defined as exercise limitation associated with significant functional impairment. * Clinically stable disease with no recent exacerbation requiring treatment modification within the previous 3 months. * Affiliation with a health insurance/social security system. * Ability to understand the study procedures and provide written informed consent. Non-inclusion Criteria: * Inability to perform cycle ergometer exercise testing. * Participation in a pulmonary rehabilitation program within the previous 6 months. * Any contraindication to exercise testing according to standard clinical practice. * Inability to provide informed consent. * Current participation in another interventional study during an exclusion period. * Pregnant or breastfeeding women. * Individuals deprived of liberty by judicial or administrative decision. * Adults under legal protection or guardianship.

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Conditions

The condition(s) this trial relates to.

interstitial lung disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Interstitial lung disease (ILD)

Contacts and locations

Locations

  • Association Dieulefit Santé

    Dieulefit, Auvergne-Rhône-Alpes, 26220, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.