New implant could curb heavy drinking for months
NCT ID NCT07433413
First seen Feb 28, 2026 · Last updated Jun 20, 2026 · Updated 18 times
Summary
This Phase 3 trial tests a naltrexone implant placed under the skin to help people with moderate to severe alcohol use disorder drink less. About 240 adults will receive either the implant or a placebo, plus counseling. Researchers will track heavy drinking days over 24 weeks to see if the implant works.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
naltrexone hydrochloride implant
What this could lead to
If successful, this implant could provide a long-lasting treatment option to help people with alcohol use disorder reduce heavy drinking days.
What could go wrong
This is a Phase 3 trial, but it hasn't started recruiting yet. The implant may not work better than placebo, and side effects like nausea or implant site reactions are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.