New implant could curb heavy drinking for months

NCT ID NCT07433413

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This Phase 3 trial tests a naltrexone implant placed under the skin to help people with moderate to severe alcohol use disorder drink less. About 240 adults will receive either the implant or a placebo, plus counseling. Researchers will track heavy drinking days over 24 weeks to see if the implant works.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
naltrexone hydrochloride implant
What this could lead to
If successful, this implant could provide a long-lasting treatment option to help people with alcohol use disorder reduce heavy drinking days.
What could go wrong
This is a Phase 3 trial, but it hasn't started recruiting yet. The implant may not work better than placebo, and side effects like nausea or implant site reactions are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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