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Which painkiller works best in spinal anesthesia? small trial aims to find out

NCT ID NCT07294352

Symptom relief Sponsor: CMH Lahore Medical College and Institute of Dentistry Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 1 time

Summary

This study compares two painkillers, nalbuphine and tramadol, added to standard spinal anesthesia for people having leg surgery. Forty adults will receive one of the two drugs, and researchers will measure how long pain relief lasts and how quickly the anesthesia takes effect. The goal is to see which option provides better pain control with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nalbuphine and tramadol (painkillers)
What this could lead to
If one drug works better, it could improve pain control and reduce side effects for people having leg surgery under spinal anesthesia.
What could go wrong
This is a small, early-stage study with only 40 people. Results may not apply to everyone, and neither drug may prove clearly better.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jan 2026

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ASA Physical Status 1 and 2 Undergoing surgical correction of lower limb fracture Exclusion Criteria: * hypersensitivity to opioids or local anesthetics patient refusal

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adjuvants, anesthesia Subarachnoid block

Contacts and locations

Locations

  • Combined Military Hospital Lahore

    Lahore, Pakistan

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