Which painkiller works best in spinal anesthesia? small trial aims to find out

NCT ID NCT07294352

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two painkillers, nalbuphine and tramadol, added to standard spinal anesthesia for people having leg surgery. Forty adults will receive one of the two drugs, and researchers will measure how long pain relief lasts and how quickly the anesthesia takes effect. The goal is to see which option provides better pain control with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nalbuphine and tramadol (painkillers)

What this could lead to

If one drug works better, it could improve pain control and reduce side effects for people having leg surgery under spinal anesthesia.

What could go wrong

This is a small, early-stage study with only 40 people. Results may not apply to everyone, and neither drug may prove clearly better.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Combined Military Hospital Lahore

    Lahore, Pakistan