New study tests how a common sedative changes brain activity during surgery

NCT ID NCT07259460

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how the drug dexmedetomidine, given through a precise infusion pump, affects brain wave monitors and pain sensors in 60 adults undergoing general anesthesia with propofol and remifentanil. Researchers want to see if changes in dexmedetomidine levels alter the Patient State Index, EEG patterns, and the Analgesia Nociception Index. The goal is to improve how doctors monitor sedation and pain during surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dexmedetomidine
What this could lead to
If successful, this could help anesthesiologists better adjust sedation and pain control during surgery, potentially improving patient safety and recovery.
What could go wrong
This is a small, early-phase observational study with only 60 participants. It does not test a new treatment or cure, so results may not change clinical practice directly.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Treviso Regional Hospital

    RECRUITING

    Treviso, TV, 31100, Italy

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