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Shivering showdown: which drug wins for surgery patients?

NCT ID NCT07543913

Symptom relief Sponsor: Sargodha Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two medicines, nalbuphine and ketamine, to see which works better at stopping shivering in women having gynecological surgery with spinal anesthesia. Shivering can cause problems like low oxygen and slow recovery. The trial included 90 women aged 18-40 and compared how well each drug controlled shivering and any side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Apr 2023

Finished

Feb 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: i. Female patients of age between 18 and 40 years undergoing gynecological surgeries (total abdominal hysterectomy, ovarian cystectomy, vaginal hysterectomy, myomectomy). ii. ASA 1 and 2. Exclusion Criteria: i. ASA 3 and onwards as per the classification of the American Society of Anesthesiologists. ii. Obstetric patients iii. Patients who are allergic to study drugs. iv. Patients undergoing general anesthesia.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Peri-operative shivering under spinal anaesthesia

Contacts and locations

Locations

  • DHQ

    Sargodha, Pakistan