Tiny nail vessels may reveal clues about psoriasis severity
NCT ID NCT07693595
First seen Jul 09, 2026 · Last updated Jul 31, 2026 · Updated 5 times
Summary
This observational study examines nailfold capillaries — tiny blood vessels at the base of the fingernails — in people with psoriasis. Researchers will use a special microscope to see if these vessels look different depending on how severe the psoriasis is. The goal is to find a simple, non-invasive way to help assess the disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If patterns are found, nailfold capillaroscopy could become a simple tool to help assess psoriasis severity or guide treatment.
- What could go wrong
- This is an observational study, not a treatment trial. It may find no clear link between nailfold changes and psoriasis severity.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study will include patients clinically diagnosed with psoriasis attending the dermatology outpatient clinics at Al-Hussein and Sayed Galal University Hospitals in Cairo, Egypt during the study period.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients clinically diagnosed with psoriasis. Exclusion Criteria: * Patients with connective tissue diseases (e.g., systemic sclerosis, SLE) * Diabetes mellitus or peripheral vascular disease * Current smokers * Pregnant or lactating women * Recent use of vasodilators or beta-blockers * Manual workers exposed to vibrating tools
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Al-Hussein University Hospital & Sayed Galal University Hospital
RECRUITINGCairo, Cairo Governorate, Egypt
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