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Brain training for better mood control: new study tests N-ACT program

NCT ID NCT06226467

Symptom relief Sponsor: University of California, Berkeley Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot trial tested a new cognitive training program called N-ACT in 50 adults with high levels of emotion-related impulsivity and rumination. Participants completed eight weekly one-hour sessions with a coach, practicing exercises to improve emotional control. The study compared those who started training right away to a waitlist group to see if the program reduced impulsive feelings and repetitive negative thinking.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cognitive training program (Neurobehavioral Affective Control Training, N-ACT)
What this could lead to
If it works, this could point toward a new non-drug approach to help people with emotional distress and mood instability.
What could go wrong
This is a small, early pilot study with only 50 participants, so results may not apply widely. The program is compared to a waitlist, not an active treatment, so any benefits could be due to attention or expectation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Nov 2024

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Current residency in the state of California * Elevated levels of rumination and/or emotion-related impulsivity Exclusion Criteria: * Insufficient English language literacy to understand study procedures (as assessed by self-report) * Careless or inattentive responding as indicated by (a) failing 50% or more of "attention check" items embedded in the online screening questionnaires, (b) overly rapid responding (i.e., mean response time of less than two seconds for multiple choice items), or (c) qualitative review of long strings of identical entries on screening/baseline questionnaire items that suggest data invalidity * Positive history of brain tumors, neurological disorders, or head injuries (with loss of consciousness more than five minutes and/or more than two separate instances of clinically-significant head trauma) * Recent (i.e., past three months) alcohol/other substance use disorders or current psychosis (as assessed by the Mini International Neuropsychiatric Interview; MINI) * Active suicidal ideation paired with either (1) plan and/or intent or (2) lifetime history of suicide attempts (as assessed by the Columbia Suicide Severity Rating Scale; C-SSRS)

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Conditions

The condition(s) this trial relates to.

Affective Symptoms Emotional Regulation Impulsive Behavior rumination disorder Rumination Syndrome Self-Control

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Affective symptoms Emotional distress Impulsive behavior Mood instability Mood lability Psychopathology Rumination

Contacts and locations

Locations

  • University of California

    Berkeley, California, 94720, United States

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