Can cheap eye drops stop Kids' nearsightedness after cataract surgery?
NCT ID NCT07364370
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether low-dose atropine eye drops (0.05%) can slow down worsening nearsightedness in children aged 1 to 7 who have had cataract surgery with an artificial lens implant. Fifty children will receive the drops for 12 months, and researchers will measure changes in their eye prescription and eye length. The goal is to find an affordable way to prevent severe nearsightedness after pediatric cataract surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Atropine 0.05% eye drops
- What this could lead to
- If it works, this could offer a low-cost way to control worsening nearsightedness in children after cataract surgery, reducing the need for strong glasses or further procedures.
- What could go wrong
- This is a small, early-stage trial with only 50 children, so results may not apply to everyone. Atropine can cause light sensitivity, blurry vision, and allergic reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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1 year to 7 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: 1. Children after IOL implantation (primary or secondary) 2. Age 1-7 years Exclusion criteria: 1. Eyes with post-operative media opacity hindering adequate assessment of refraction 2. Eyes with complicated surgeries (e.g. vitreous loss, dropped lens matter requiring PPV, retinal detachment, etc) 3. Retinal pathologies 4. Glaucoma (congenital or secondary to surgery) 5. Anterior or posterior segment anomalies
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cairo University
Cairo, 11965, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A new lens design might stop adult nearsightedness from worsening
- Special lenses may curb worsening nearsightedness in kids
- Could special glasses stop nearsightedness from getting worse?
- Eye drops could keep Kids' vision from getting worse
- New glasses film aims to stop kids' eyesight from getting worse
- New glasses for nearsighted kids put to the test