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Fibroid surgery may change uterine blood flow – new study investigates

NCT ID NCT07343765

Knowledge-focused Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether surgically removing uterine fibroids (myomectomy) changes blood flow in the main uterine artery. Researchers will use Doppler ultrasound to measure blood flow before and about 40 days after surgery in 70 premenopausal women. The goal is to provide new insights into how fibroid removal affects uterine blood supply, which could help improve future care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
myomectomy (surgical removal of uterine fibroids)
What this could lead to
If successful, this study could help doctors better understand how fibroid removal affects uterine blood flow, potentially guiding future treatment and follow-up plans.
What could go wrong
This is a small, early-stage observational study with only 70 participants. It measures blood flow patterns, not direct health outcomes, so results may not change clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Feb 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients scheduled for myomectomy at the Obstetrics and Gynecology Clinic of our hospital

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Premenopausal women aged between 18 and 50 years. * Women with uterine leiomyoma detected via ultrasonography. * Patients referred to the Obstetrics and Gynecology department board for whom a myomectomy operation has been decided. * Women who provide consent for transvaginal ultrasound examination. Exclusion Criteria: * Women under 18 years of age and postmenopausal women. * Current pregnancy or postpartum status. * Presence of known circulatory disorders, cardiovascular diseases, or other chronic conditions affecting blood flow. * Smokers. * Current use of hormonal medications (e.g., oral contraceptives, levonorgestrel-releasing intrauterine devices, etc.). * Presence of concurrent gynecological pathologies (e.g., adenomyosis, endometriosis, ovarian cysts, or gynecological malignancies).

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Conditions

The condition(s) this trial relates to.

leiomyoma uterine corpus leiomyoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Doppler ultrasound Leiomyoma (uterine fibroids) Myomectomy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bakırköy Dr Sadi Konuk Eğitim ve Araştırma Hastanesi

    Istanbul, bakırköy, 34147, Turkey (Türkiye)

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