Ice pack on the belly may ease pain after keyhole hysterectomy
NCT ID NCT07626684
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether applying an ice pack to the lower abdomen after vNOTES hysterectomy can lower pain and reduce the need for painkillers. 122 women having surgery for benign conditions will be randomly assigned to receive either standard care or standard care plus ice packs for 20 minutes every two hours during the first day after surgery. The goal is to see if this simple, low-cost approach improves comfort and speeds recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- abdominal ice pack
- What this could lead to
- If it works, this could provide a simple, drug-free way to ease pain and speed recovery after vNOTES hysterectomy.
- What could go wrong
- This is a small, early-stage trial. The ice pack may not significantly reduce pain or improve bowel function, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 122 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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48 to 70 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Scheduled to undergo elective vaginal natural orifice transluminal endoscopic surgery hysterectomy. * Patients with benign gynecological indications including uterine leiomyoma, adenomyosis, or abnormal uterine bleeding. * Patients with premalignant gynecological indications including atypical endometrial hyperplasia or cervical intraepithelial neoplasia. * Patients managed strictly under the standardized institutional Enhanced Recovery After Surgery protocol. * Patients with an American Society of Anesthesiologists physical status classification of I or II. * Patients who demonstrate adequate cognitive capacity to understand and utilize the Visual Analog Scale and Face Pain Index. * Patients who voluntarily provide signed written informed consent prior to participating in the clinical study. Exclusion Criteria: * Patients with a documented history of chronic pelvic pain or systemic chronic pain syndromes. * Patients with known hypersensitivity, allergy, cold urticaria, or intolerance to local cryotherapy or cold applications. * Patients with a history of prior major open abdominal surgery * Active pregnancy, suspected pregnancy, or current lactation status at the time of enrollment. * Patients with severe systemic diseases including uncontrolled diabetes mellitus, severe hepatic impairment, or end-stage renal disease. * Coagulation disorders, active bleeding diathesis, or patients on mandatory continuous anticoagulant therapy. * Diagnosed psychiatric disorders, severe depression, anxiety, or cognitive impairment preventing valid clinical outcome scoring. * Intraoperative conversion from vaginal natural orifice transluminal endoscopic surgery to conventional laparoscopy or open laparotomy. * Patients experiencing major intraoperative complications including severe vascular, bladder, bowel, or ureteral injury. * Patients requiring perioperative blood product transfusion due to significant estimated blood loss during surgery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Mugla Sitki Kocman University
Muğla, 48000, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Weight-Loss drug boost Fertility-Sparing cancer treatment?
- Can big data improve safety in gynecologic surgery?