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Ice pack on the belly may ease pain after keyhole hysterectomy

NCT ID NCT07626684

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether applying an ice pack to the lower abdomen after vNOTES hysterectomy can lower pain and reduce the need for painkillers. 122 women having surgery for benign conditions will be randomly assigned to receive either standard care or standard care plus ice packs for 20 minutes every two hours during the first day after surgery. The goal is to see if this simple, low-cost approach improves comfort and speeds recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
abdominal ice pack
What this could lead to
If it works, this could provide a simple, drug-free way to ease pain and speed recovery after vNOTES hysterectomy.
What could go wrong
This is a small, early-stage trial. The ice pack may not significantly reduce pain or improve bowel function, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 122 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

48 to 70 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Scheduled to undergo elective vaginal natural orifice transluminal endoscopic surgery hysterectomy. * Patients with benign gynecological indications including uterine leiomyoma, adenomyosis, or abnormal uterine bleeding. * Patients with premalignant gynecological indications including atypical endometrial hyperplasia or cervical intraepithelial neoplasia. * Patients managed strictly under the standardized institutional Enhanced Recovery After Surgery protocol. * Patients with an American Society of Anesthesiologists physical status classification of I or II. * Patients who demonstrate adequate cognitive capacity to understand and utilize the Visual Analog Scale and Face Pain Index. * Patients who voluntarily provide signed written informed consent prior to participating in the clinical study. Exclusion Criteria: * Patients with a documented history of chronic pelvic pain or systemic chronic pain syndromes. * Patients with known hypersensitivity, allergy, cold urticaria, or intolerance to local cryotherapy or cold applications. * Patients with a history of prior major open abdominal surgery * Active pregnancy, suspected pregnancy, or current lactation status at the time of enrollment. * Patients with severe systemic diseases including uncontrolled diabetes mellitus, severe hepatic impairment, or end-stage renal disease. * Coagulation disorders, active bleeding diathesis, or patients on mandatory continuous anticoagulant therapy. * Diagnosed psychiatric disorders, severe depression, anxiety, or cognitive impairment preventing valid clinical outcome scoring. * Intraoperative conversion from vaginal natural orifice transluminal endoscopic surgery to conventional laparoscopy or open laparotomy. * Patients experiencing major intraoperative complications including severe vascular, bladder, bowel, or ureteral injury. * Patients requiring perioperative blood product transfusion due to significant estimated blood loss during surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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Contacts and locations

Locations

  • Mugla Sitki Kocman University

    Muğla, 48000, Turkey (Türkiye)

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