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New online program aims to lift depression in MS patients

NCT ID NCT07636434

Symptom relief Sponsor: University of Washington Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether an internet-based program called My MS Toolkit can help reduce depression in people with multiple sclerosis. The toolkit teaches skills based on cognitive behavioral therapy to manage common MS symptoms like fatigue, pain, and low mood. Researchers will compare depression severity between 110 adults who use the toolkit and those who receive usual care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
My MS Toolkit (online self-management program based on cognitive behavioral therapy)
What this could lead to
If it works, this could provide a practical, accessible way for people with MS to manage depression symptoms from home.
What could go wrong
This is a small, early-stage trial (110 people) testing a digital tool, not a drug. Results may not apply to everyone, and the program may not be more helpful than usual care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 110 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Self-reported diagnosis of MS (with screening questions such as current disease modifying therapy) * At least 18 years of age * Can read, write, and speak in English * Score of \>4 on the Patient Health Questionnaire, indicating at least mild depressive symptoms * Have access to an internet-connected device for accessing the intervention Exclusion Criteria: * Previous diagnosis of bipolar disorder or schizophrenia * Started medication for depression or anxiety in the past 2 months * Currently undergoing psychotherapy for depression * Are of moderate or high risk for suicide on the Columbia Suicide Severity Rating Scale (C-SSRS) * Participating in another clinical trial

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Conditions

The condition(s) this trial relates to.

Depression multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis Multiple sclerosis (MS)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    1 site. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • University of Washington

    Seattle, Washington, 98133, United States

    Contact Email: •••••@•••••

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