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Can a simple 8-Week program keep your brain sharp?

NCT ID NCT07424443

Prevention Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an 8-week group program called My Healthy Brain for adults aged 50 and older who have memory concerns but not dementia. The program teaches about lifestyle factors like exercise, sleep, and diet that may help prevent dementia. Researchers want to see if the program is practical and well-liked by participants in senior centers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
My Healthy Brain program (behavioral intervention)
What this could lead to
If successful, this program could offer a practical, community-based approach to help older adults reduce their risk of dementia through lifestyle changes.
What could go wrong
This is a small pilot study with only 60 participants, so results may not apply to everyone. The program is behavioral, so benefits depend on individual motivation and adherence.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged ≥ 50 * Subjective cognitive decline (SCD; e.g., forgetting information, getting lost, and repeating oneself) * Able to self-identify at least 1 modifiable lifestyle risk factors for dementia to change during the program (physically inactive, poor sleep, non-adherence to Mediterranean diet, alcohol use, tobacco use, socially isolated or lonely, mental inactivity) * Absence of significant cognitive impairment (assessed using Short Blessed Test71 ≤ 9) * Self-reported English proficiency/literacy * Ability and willingness to participate and complete all study-related activities Exclusion Criteria: * Dementia or other neurodegenerative disease per patient self-report or disclosure * Psychosis, uncontrolled schizophrenia or schizoaffective disorder, uncontrolled bipolar disorder, or uncontrolled substance dependence/abuse * Active self-report of suicidal ideation / high risk of suicide * Serious medical illness expected to worsen during the study * Self-reported safety issues with initiating lifestyle change

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Conditions

The condition(s) this trial relates to.

Alcohol Drinking Alzheimer disease Memory Disorders Motor Activity Risk Reduction Behavior Sedentary Behavior Smoking subjective cognitive decline dementia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dementia prevention Healthy lifestyle behaviors Lifestyle (sedentary behavior and physical activity) Lifestyle risk reduction Memory loss (excluding dementia)

Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.