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Rhythm and connection: music therapy shows promise for dementia patients and caregivers

NCT ID NCT06768996

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores whether a simple music activity—tapping along to rhythms together—can improve social attention and feelings of closeness in people with frontotemporal dementia or Alzheimer's disease, and their caregivers. Eighty patient-caregiver pairs will participate in a controlled experiment. The goal is to see if shared rhythm-making boosts social skills and relationship quality, and to understand which brain networks might be involved.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Synchronous rhythm production (a musical activity where participants tap along to rhythms)
What this could lead to
If it works, this could point toward a simple, enjoyable way to improve social connection and attention for people with dementia and their caregivers.
What could go wrong
This is a small, early exploratory study with only 80 participants, so results may not apply to everyone. The benefits may be modest or not last long.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Jan 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 89 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion (patients) * Male or female ≥ 55 years of age living with bvFTD; or ≥ 70 years of age living with AD. * Documentation of a bvFTD or AD diagnosis as evidenced by one or more known clinical features. * Written informed consent obtained from subject. Inclusion (caregivers) * Male or female ≥ 55 years of age living without diagnosis of neurological or psychiatric disease. * Individual capable of independent execution of activities of daily living, including personal care and hygiene, dressing, eating, use of a toilet, and mobility. * Written informed consent. Exclusion (patients) * Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data. * community-dwelling individuals not living with bvFTD * community-dwelling individuals with normal cognitive functioning * Individuals living with Alzheimer's disease or related dementias (primary progressive aphasia, semantic variant FTD, Lewy body dementia, vascular dementia, Parkinson's disease, or mixed dementia) * Individuals with a score of 2 or higher on the CDR * Individuals with a history of neuropsychiatric illness that would interfere with performance (e.g., transient psych hx of depression okay, hx of schizophrenia will be excluded) or medicated depression to control symptoms. * Individuals with unstable (e.g., cancer other than basal cell skin) or chronic (e.g., severe diabetes) medical conditions * Individuals with MRI contraindications (e.g., pregnancy, claustrophobia, metal implants that are contraindicated for MRI) * Individuals with physical impairment(s) precluding motor response * Individuals with inability to walk two blocks without stopping * Individuals with hearing or vision deficits that will not allow for completion of testing; inability to hear conversation conducted at an average volume (\~60 dB) * Individuals who practice music making or production for at least 30-mins per week * This may include instrumental or vocal, writing or arranging, alone or in groups * Listening to music for more than 30-mins weekly will not exclude the individual from the study Exclusion (Caregivers) * Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data. * Community-dwelling individuals living with diagnosis of a neurological or psychiatric disease o Community-dwelling individuals with abnormal cognitive functioning * Individuals living with dementia * Individuals with a history of neuropsychiatric illness that would interfere with performance (e.g., transient psych hx of depression okay, hx of schizophrenia will be excluded) or medicated depression to control symptoms * Individuals with unstable (e.g., cancer other than basal cell carcinoma) or chronic (e.g., severe diabetes) medical conditions * Individuals with physical impairment(s) precluding motor control * Individuals with inability to walk two blocks without stopping * Individuals with hearing or vision deficits that will not allow for completion of testing; inability to hear conversation conducted at an average volume (\~60 dB) * Individuals who practice music making or production for at least 30-mins per week * This may include instrumental or vocal, writing or arranging, alone or in groups * Listening to music for more than 30-mins weekly will not exclude the individual from the study

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sandler Neurosciences Center

    San Francisco, California, 94158, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.