Soothing sounds for sensitive stomachs: music therapy tested for IBS pain
NCT ID NCT06706778
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This pilot study from Yale University will test whether listening to calming, instrumental music can reduce pain and stress in people with irritable bowel syndrome (IBS). Thirty adults with moderate IBS pain will listen to pre-recorded playlists for 20 minutes twice a day, five days a week, for four weeks. Researchers will measure pain, stress, and gut bacteria changes using wearable sensors and questionnaires to understand how music might help.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Music intervention (listening to pre-recorded instrumental playlists)
- What this could lead to
- If it works, this could point toward a simple, drug-free way to ease IBS pain and stress at home.
- What could go wrong
- This is a very small pilot study with only 30 people and no comparison group. It is designed to test feasibility and mechanisms, not to prove effectiveness. Results may not apply to everyone with IBS.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * aged between 18 and 50 years old, * can speak and read English, * having a confirmed diagnosis of IBS from a healthcare provider, * having experienced moderate pain (≥3 out of 10 on a numeric rating scale) at least four days a week for the past three months, * be willing to participate in a 4-week intervention and attend two lab visits, and * having daily access to an internet-enabled device for MBI. Exclusion Criteria: * having a severe psychiatric disorder requiring inpatient treatment in the past six months, * regularly using opioids or illicit substances, or have used probiotics or antibiotics within two weeks prior to enrollment, * having celiac disease, inflammatory bowel disease, or a history of major gastrointestinal surgery, * concurrently participate in another IBS-related intervention study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Yale School of Nursing
New Haven, Connecticut, 06477, United States
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