Headphones in the OR: music may tame surgical stress
NCT ID NCT06166186
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 37 times
Summary
This study tested whether playing music through headphones during liver donation surgery could lower the body's stress and inflammation response. Sixty-one adult donors were randomly assigned to hear music or silence from the start of anesthesia until waking up. Researchers measured inflammatory markers like interleukin-6 and TNF-alpha in blood samples taken before and after surgery.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Istinye University Hospital
Istanbul, Turkey (Türkiye)
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
music
What this could lead to
If it works, this could point toward a simple, drug-free way to reduce stress and inflammation during surgery.
What could go wrong
This is a small, completed study with only 61 participants. The results may not apply to all surgeries or patients, and the effect may be too small to matter.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.