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Music during surgery may tame stress and inflammation

NCT ID NCT06166186

Symptom relief Sponsor: Istinye University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether playing music through headphones during liver donation surgery could reduce the body's stress and inflammation response. 61 adult liver donors were randomly assigned to hear music or no music during their operation. Researchers measured inflammatory markers like interleukin-6 and TNF-alpha in blood samples taken before and after surgery to see if music made a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
music
What this could lead to
If it works, this could point toward a simple, drug-free way to reduce stress and inflammation during major surgery.
What could go wrong
This is a small, completed study with only 61 participants. The results may not apply to all surgeries or patients, and the effect of music on inflammation is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

61 people

The number who actually took part.

Started

May 2023

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing donor hepatectomy * American Society of Anesthesiologists class 1 to 2 * Ability to consent Exclusion Criteria: * American Society of Anesthesiologists greater than 2 * Documented or known sensitivity to any drug to be used in the study. * Patient with immunosuppressant/ cytotoxic/ steroid therapy. * not understand the aim and objectives of the study

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Conditions

The condition(s) this trial relates to.

Fractures, Stress

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hepatectomy MUSIC Stress response Transplantation

Contacts and locations

Locations

  • Istinye University Hospital

    Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.