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Leg strength may be key to heart health in rare condition

NCT ID NCT07420660

First seen Feb 23, 2026 · Last updated Jun 23, 2026 · Updated 18 times

Summary

This study looks at how leg muscle size and strength affect circulation in people born with a single-chamber heart, a condition where the heart can't pump blood to the lungs on its own. Researchers will measure muscle mass, oxygen use, and quality of life in 40 adults aged 16-50 who have had the Fontan procedure. The goal is to understand the link between muscles and circulation, which could lead to better exercise programs for these patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could lead to better exercise recommendations and muscle-strengthening programs to improve circulation and quality of life for people with single-chamber hearts.

What could go wrong

This is an observational study with only 40 participants, so results may not apply to everyone. It aims to understand the problem, not test a treatment, so direct benefits are uncertain.

Conditions

The condition(s) this trial relates to.

congenital heart disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.