New study uses 3D ultrasound to unravel muscle mysteries in cerebral palsy
NCT ID NCT05197764
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to understand how muscles change over time in children with spastic cerebral palsy. Researchers will use 3D ultrasound to measure muscle size, length, and quality in 229 children. The goal is to link these changes to brain injury and treatments, helping improve future care.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 229 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2019
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Children with spastic cerebral palsy, who have routine follow-up care at the CP reference center of the University Hospitals Leuven, the rehabilitation centers of Pulderbos and/or Inkendaal
- Ages
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6 months to 9 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Confirmed diagnosis of spastic cerebral palsy or patients at high-risk for spastic cerebral palsy * Suspected GMFCS levels I-III (GMFCS = Gross Motor Function Classification Scale, expressing the overall functional level of impairment) Exclusion Criteria: * Non-ambulatory * Botulinum neurotoxin type-A injections six months prior to enrollment * Lower limb surgery two years prior to enrollment * Muscle surgery at the muscles in the lower limb * Selective dorsal rhizotomy as treatment history * Presence of ataxia or dystonia * Severe co-morbidities (severe epilepsy, severe behavior problems that impede the cooperation)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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UZ Leuven
RECRUITINGLeuven, Vlaams-Brabant, 3000, Belgium
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can virtual reality help children with brain injury regain hand control?
- Zapping the spine: a Non-Invasive device aims to loosen stiff muscles and improve walking in cerebral palsy
- Can a moving platform help kids with cerebral palsy steady their steps?
- Biofeedback may unlock stronger muscles in children with cerebral palsy
- Can video games rebuild arm strength in cerebral palsy?
- Virtual reality vs. strength training: which boosts arm function in cerebral palsy?