New MRI technique could shed light on rare kidney disease
NCT ID NCT05682053
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a special type of MRI can detect early changes in the kidneys of people with medullary sponge kidney, a rare condition that can cause kidney stones. Researchers compared MRI scans from 33 adults with the disease to scans from healthy controls. The goal was to see if the MRI could spot problems in the kidney's inner tissue, which could help with earlier diagnosis and better understanding of the disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to earlier diagnosis and a better understanding of how medullary sponge kidney affects the kidneys.
- What could go wrong
- This is a small, early-stage study that only looks at imaging results, not a treatment. The findings may not lead to any direct changes in patient care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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33 people
The number who actually took part.
- Started
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Mar 2023
- Finished
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Jan 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * medullary sponge kidney attending medical consultation * Patients with glomerular filtration rate \> 60 mL/min/1.73m2 without kidney stone * consent signed * effective contraceptive method for women * affiliated to social insurance scheme Exclusion Criteria: * kidney transplant * polycystic kidney diseases * Chronic kidney disease (GFR \< 60 mL/min/1,73m² ) * MRI contraindications (claustrophobia, pacemaker, cardioverter defibrillators implantable, mechanical heart valve non MRI-compatible) * Weight\> 130 kg * pregnancy * legal protection measure (guardianship, curatorship) * Deprived of liberty by a judicial or administrative decision * subject participating in another research that may interfere with the research and including an exclusion period still in progress at inclusion
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Edouard Herriot
Lyon, 69003, France