New combo therapy may help spina bifida kids stay dry
NCT ID NCT07338799
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a mix of treatments—biofeedback, osteopathic care, behavioral training, diet changes, and electrical stimulation—to help children with spina bifida control their bladder. 66 kids aged 10-17 took part, receiving either the combo therapy or standard care for 10 weeks, with a 12-week follow-up. The goal was to reduce daily wetting accidents and improve quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Multimodal therapy including biofeedback, osteopathic procedures, behavioral training, diet control, and electrical stimulation
- What this could lead to
- If successful, this approach could offer a non-drug way to help children with spina bifida gain better bladder control and improve their quality of life.
- What could go wrong
- This is a small, completed trial with only 66 participants, so results may not apply to all children. The therapy is complex and requires commitment, which may limit real-world use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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66 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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10 to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * = children with lower lumbar or sacral myelomeningocele spina bifida, * urinary incontinence due to neurogenic bladder dysfunction * the ability to understand and adhere to study procedures * :intelligence required to be engaged in biofeedback and behavioural training activities Exclusion Criteria * thoracic or high lumbar myelomeningocele, and other forms of spina bifida with complete sacral loss of innervation * severe cognitive or behavioral impairments likely to interfere with adherence to training regimens * uncontrolled epilepsy and severe musculoskeletal deformities that could not allow the placement of the electrode or postural exercises. * The participants that had undergone urological or neurosurgical operation in the past six months and those who were undergoing botulinum toxin injection or sacral neuromodulation therapy were also disqualified
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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faculty of physical therapy, Cairo University
Cairo, Cairo Governorate, P.O.Box 11432, Egypt