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New combo therapy may ease shoulder pain in breast cancer survivors

NCT ID NCT02735668

Symptom relief Sponsor: University of Alcala Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a combination of physiotherapy techniques—including dry needling, nerve gliding exercises, and scapula strengthening—works better than exercise alone for women with ongoing shoulder pain after breast cancer treatment. Ninety women were randomly assigned to one of three groups: multimodal physiotherapy, scapula exercises, or conventional shoulder exercises. The goal was to see which approach best reduced pain and disability and improved quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
multimodal physiotherapy (dry needling, neurodynamic techniques, and scapula exercises)
What this could lead to
If successful, this could offer a more effective, non-drug approach to ease persistent shoulder pain and improve quality of life in breast cancer survivors.
What could go wrong
This is a small, completed trial with 90 participants, so results may not apply to all women. The intervention is complex and requires skilled therapists, limiting widespread use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Apr 2016

Finished

Apr 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women with peripheral persistent pain following breast cancer treatment (surgery and/or radiotherapy and/or chemotherapy) with pain for at least 6 months. * Women who do not present contraindications for physiotherapy (infection, metastasis, locoregional recurrence). * Women who have read, understood and signed informed consent freely Exclusion Criteria: * Women treated with bilateral breast cancer. * Women with shoulder pain episodes prior to breast cancer treatment. * Women with predominant central sensitization pain identified by the Central Sensitization Inventory (\> 40 points) * Women with cognitive limitations to understand the information provided, instructions for treatment and consent to their participation in the study.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Shoulder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Shoulder pain

Contacts and locations

Locations

  • Teacher care and research in physiotherapy Unit. Department of Physiotherapy. University of Alcala.

    Alcalá de Henares, Madrid, 28871, Spain

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