Simple blood test could spot multiple cancers early
NCT ID NCT07598747
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a new blood test that looks for DNA from cancer cells. The goal is to see if an artificial intelligence program can accurately detect many different types of cancer at an early stage. The study will include 6,000 adults, some with cancer and some healthy volunteers, to see how well the test works.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- blood test (circulating DNA analysis with artificial intelligence)
- What this could lead to
- If successful, this could lead to a simple blood test that catches many types of cancer early, when they are easier to treat.
- What could go wrong
- This is an early-stage study focused on developing and validating the test. It is not yet proven to work in the real world, and there is a risk of false positives or false negatives.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 6,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2024
- Expected to finish
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Oct 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Cancer patients 5,000, Healthy volunteers: 1,000
- Ages
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19 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adults aged 19 years or older 2. Individuals who understand the study and voluntarily provide informed consent. 3. (only for cancer participants) Participants with newly diagnosed solid tumors (Stage I-IV, including brain tumors) or hematologic malignancies who: * Have a histologically confirmed diagnosis (including bone marrow biopsy), or * Are highly suspected of having cancer based on clinical and/or radiologic evaluation and are scheduled for surgical resection after blood collection; and * Have not yet initiated any treatment (chemotherapy, targeted therapy, hormonal therapy, immunotherapy, radiotherapy, surgical resection, etc.). 4. (only for non-cancer participants) Individuals with no prior history of cancer. 5. (only for non-cancer participants) Individuals scheduled to undergo chest and/or abdominal CT or MRI imaging. Exclusion Criteria: 1. Pregnancy (self-reported pregnancy status). 2. Individuals for whom blood collection is deemed difficult by the investigator. 3. Individuals with a history of infection with HIV, HTLV, or syphilis. 4. (only for non-cancer participants) Individuals diagnosed with another malignancy within the past 5 years (exceptions: non-melanoma skin cancer, in-situ malignancies, thyroid cancer, and cervical intraepithelial neoplasia treated with curative intent). 5. (only for non-cancer participants) Individuals with cancer of unknown primary origin. 6. (only for non-cancer participants) Individuals with synchronous or metachronous multiple primary cancers.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Yonsei Cancer Center
RECRUITINGSeoul, 03722, South Korea
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