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New device could speed up GERD diagnosis and save billions
NCT ID NCT07227506
First seen Jun 25, 2026 · Last updated Jul 28, 2026 · Updated 3 times
Summary
This study tests a new FDA-approved device called MuVI that measures electrical resistance in the esophagus to diagnose GERD and eosinophilic esophagitis. Researchers will enroll 50 adults with chronic esophageal symptoms who are already scheduled for an upper endoscopy. The goal is to see if this device can diagnose these conditions more accurately and cost-effectively than current methods, potentially reducing the need for multiple procedures.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- MuVI Esophageal mucosal impedance testing device
- What this could lead to
- If successful, this device could provide a faster, cheaper, and more accurate way to diagnose GERD and eosinophilic esophagitis, reducing the need for multiple procedures.
- What could go wrong
- This is a small early study with only 50 participants, so results may not apply to everyone. The device may not be more accurate than current tests.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All the patients with reflux symptoms or dysphagia/esophageal symptoms who undergo upper endoscopy will be enrolled into the study.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1\. Patients with chronic esophageal symptoms such as atypical or typical reflux symptoms and dysphagia, is here for upper endoscopy testing. Exclusion Criteria: 1. Presence of esophageal stricture 2. Unstable patients who cannot undergo this testing. 3. Patients on anticoagulation on the day of procedure. 4. Presence of esophageal cancer. 5. Pregnancy. 6. Minor patients.
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Froedtert Hospital
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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