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MS frailty study seeks clues in blood and balance

NCT ID NCT07521982

Knowledge-focused Sponsor: Baskent University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will compare frailty, physical fitness, and levels of a hormone called irisin in 782 people with multiple sclerosis and healthy volunteers aged 18-65. Researchers will use tests like the Frailty Index, Berg Balance Scale, and 6-Minute Walk Test, along with blood samples. The goal is to better understand frailty in MS and guide future rehabilitation strategies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help identify biomarkers and targets for rehabilitation strategies to manage frailty in multiple sclerosis.
What could go wrong
This is an observational study, not a treatment trial. It will not directly improve health, and results may not lead to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 782 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients aged 18-65 diagnosed with MS who applied to the Başkent University Alanya Hospital Center Physical Medicine and Rehabilitation outpatient clinic between April 1, 2026, and May 30 2026, and healthy volunteers aged 18-65 years with similar demographic characteristics (age, gender, etc.) will be included.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-65 evaluated by neurology and diagnosed with definitive MS via objective methods (MRI, lumbar puncture, etc.). * Healthy volunteers aged 18-65. * Being literate in Turkish. * Participants who provide a consent form to participate in the study. Exclusion Criteria: * Being younger than 18 or older than 65. * Presence of any concomitant neurological disease other than MS. * Presence of an uncontrolled systemic disease at a level that would affect the evaluation. * Presence of cognitive impairment or psychiatric illness at a level that would affect the evaluation. * Having had an MS attack or received steroid treatment in the last month. * Presence of an orthopedic disability that prevents evaluations.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis Muscle Weakness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multipl sclerosi̇S

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Baskent University Alanya Hospital

    Antalya, Alanya, 07400, Turkey (Türkiye)

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