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Massive biobank launches to unlock secrets of MS and related disorders

NCT ID NCT00445367

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is creating a large, long-term collection of blood samples and health information from over 3,200 people with multiple sclerosis and related demyelinating diseases, as well as healthy volunteers. The goal is to provide scientists with a shared resource to better understand what causes these diseases, identify different subtypes, and discover biomarkers. Participants provide blood samples and medical data, but this study does not test any new treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

3,226 people

The number who actually took part.

Start date

May 2006

Expected to finish

Oct 2036

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Subjects with MS, selected other demyelinating diseases (Transverse Myelitis (TM), Neuromyelitis Optica (NMO) or Devic's, Acute Disseminated Encephalomyelitis (ADEM), and Optic Neuritis (ON)), and related and unrelated unaffected controls.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age 18+ able to give informed consent or individuals younger than 18 with parental permission and able to give assent * willing to provide up to 110 ml (50 ml for \< 18 years old) of blood via venipuncture * experienced at least one CNS demyelinating event characteristic of MS, TM, NMO, ADEM, or ON Exclusion Criteria: * history of blood borne pathogens * allogeneic bone marrow transplant * clinical or radiological evidence of stroke, meningitis, or other well characterized diseases of the nervous system (with the exception of MS, TM, NMO, ADEM, or ON). * weight less than 37 pounds

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Barrow Neurological Institute

    Phoenix, Arizona, 85013, United States

  • Beth Israel Deaconess

    Boston, Massachusetts, 02215, United States

  • Johns Hopkins

    Baltimore, Maryland, 21287, United States

  • Multiple Sclerosis Research Center of New York

    New York, New York, 10019, United States

  • Shepherd Center

    Atlanta, Georgia, 30309, United States

  • Stanford University

    Stanford, California, 94305, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • The Rocky Mountain MS Center at Anschutz Medical Campus at UC Denver

    Aurora, Colorado, 80045, United States

  • University of Massachusetts Medical School

    Worcester, Massachusetts, 01605, United States

  • University of Texas Southwestern Medical Center at Dallas

    Dallas, Texas, 76051, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.