Can MS treatments protect the mind as well as the body?
NCT ID NCT01392872
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This study follows people with relapsing-remitting multiple sclerosis who are starting immunosuppressant treatment. Researchers will track changes in cognitive abilities, fatigue, emotions, and overall quality of life over an extended period. The goal is to better understand how these treatments impact daily functioning beyond physical symptoms.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Immunosuppressant treatment (as part of standard care) with neuropsychological assessments
- What this could lead to
- If successful, this could clarify how immunosuppressant treatments affect thinking, fatigue, and daily life in people with relapsing-remitting MS, helping guide more informed treatment decisions.
- What could go wrong
- This is a small observational study (48 participants) without a comparison group, so results may not apply broadly. It does not test a new drug, and findings may not change clinical practice directly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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48 people
The number who actually took part.
- Start date
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Nov 2009
- Finished
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Jan 2016
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Clinical diagnosis of Relapsing MS since at least 6 months and less than 10 years * Neurological state stable since at least 1 month * Moderate Handicap (EDSS ≤ 5,5) Exclusion Criteria: * Secondary Progressive MS * Patient having an attack * Patient having experienced en MS relapse or recovered systemic corticosteroid in the previous 1 month * Depressive patient
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France
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